Endocrine Abstracts

Aim: Non-alcoholic steatohepatitis is one of the most common causes of chronic liver disease and the incidence in the population varies from %10–24. TGF- β –1 is the most important TGF- β isoform responsible for fibrosis and its effect on hepatic fibrosis was demonstrated in-vitro and in chronic viral hepatitis. Besides TGF- β is an immunsuppresive cytokine and it is known that low TGF- β activity can trigger autoimmune diseases and inflammation.<...